Meta-analysis In Medicine

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Representational image: Pexels
The use of meta-analysis in medicine has brought about a welcome transformation, notwithstanding its limitations.

You need not go too far to pool in understanding from perplexing scientific studies. To highlight a few examples—the famed oat bran story, a ‘miracle’ called wheat grass, the garlic revolution, the caffeine complexity, or the great coconut and ginseng saga. Yes, the list is in no way complete, yet it proves a point—that the promise of science, or medicine, as an arbiter of truth may not be all-encompassing.

First things first—let us delve into the oat bran saga. The whole drama began in the 1980s, when a handful of researchers, taking a ‘cue’ from past research and expanding on them, suggested that the water-soluble fibre in oat bran could lower cholesterol levels. Things reached the crescendo when 8-Week Cholesterol Cure, a revolutionary book by best-selling author, Robert E Kowalski (1942-2007), proclaimed the wonderful ‘medicinal’ qualities of oat bran.

This bid fair to yet another scientific review of high-fibre diet studies, with oat bran and beans. Oat bran was bestowed with a ‘good certificate’ from The Journal of the American Medical Association (JAMA)—this was a major scientific avowal, emerging as it did from a well-respected, peer-reviewed publication. It underlined why oat bran was special—because it was extremely ‘cost-effective’ than any other ‘treatment’ form available for high cholesterol levels. The spin-off was imminent. Sales of oat bran reached astounding levels, so much so there was trouble keeping in step with its ever-increasing demand.



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